Your current location:HOME >travel >Protein markers tied to chemotherapy success 正文
TIME:2024-05-21 17:45:51 Source: Internet compilationEdit:travel
Doctors in Shanghai have screened two protein markers to determine pancreatic cancer patients' s
Doctors in Shanghai have screened two protein markers to determine pancreatic cancer patients' sensitivity to chemotherapy, which may rewrite current treatment guidelines and improve patients' overall survival rate.
The team of researchers from Shanghai Ruijin Hospital said on Monday that the results of the study have been validated in three groups at home and abroad, showing strong clinical applicability.
A paper about the study was published as the cover article in the top international medical journal Nature Medicine on March 19.
More than 330,000 people die from pancreatic cancer worldwide each year, with an overall five-year survival rate of approximately 6 percent, according to the hospital.
By analyzing the data of 191 patients over more than three years of follow-ups, the researchers constructed a prognostic prediction model for pancreatic cancer, and identified two protein markers — NDUFB8 and CEMIP2 — which are able to accurately predict patients' sensitivity to chemotherapy.
Results of the study were independently verified among people with pancreatic cancer in and around Paris, France, and at Fudan University Shanghai Cancer Center and Shanghai Changhai Hospital.
"The research answered one of the two main queries that are current bottlenecks in the field of pancreatic cancer treatment: Which patients are sensitive to chemotherapy and which chemotherapy drugs are they sensitive to?" said Shen Baiyong, a professor at the Pancreatic Disease Diagnosis and Treatment Center of Ruijin Hospital and a leading researcher on the team.
What a blast to work at NASA. Space agency is sky2024-05-21 17:13
US says China helping Moscow in biggest defence expansion since Soviet era2024-05-21 17:01
Biden says he expects Iran to attack Israel soon, warns: 'Don't'2024-05-21 16:57
Taiwan earthquake injuries top 1000, missing hotel workers found2024-05-21 16:49
Jon Wysocki dead at 53: Staind drummer passes away2024-05-21 16:31
Woman and child escape Auckland house fire, gang at scene2024-05-21 16:25
Wellington job market already tough before public sector redundancies2024-05-21 16:10
Pure Tūroa gets 102024-05-21 15:41
A warrant for Netanyahu’s arrest was requested. But no decision was made about whether to issue it2024-05-21 15:35
More than 350 school building projects under review, Ministry of Education documents show2024-05-21 15:29
Election 2024: Biden and Trump bypassed the Commission on Presidential Debates2024-05-21 17:31
What is happening with the NZ housing market this week?2024-05-21 17:30
Impossible decisions and the job he never got to do2024-05-21 15:55
Analysis: The coalition announcement was a three2024-05-21 15:54
Liverpool confirms Arne Slot as Jurgen Klopp's replacement2024-05-21 15:40
David Seymour denies overstepping with attack on TVNZ journalist2024-05-21 15:38
NZ brothers remain behind bars after appearing in Phuket court2024-05-21 15:30
New operators of Tūroa Ski Field reveal discounts for former life2024-05-21 15:08
Company wins court ruling to continue development of Michigan factory serving EV industry2024-05-21 15:04
Coalition talks stretch on one month past election day2024-05-21 15:00